Product Pathways - Development
SSEA4 (MC813) Mouse mAb #4755
|4755S||100 µl (200 tests)||---||In Stock||---|
|4755P||40 µl (80 tests)||---||In Stock||---|
|4755||carrier free and custom formulation / quantity||email request|
Applications Key: IF-IC=Immunofluorescence (Immunocytochemistry), F=Flow Cytometry
Specificity / Sensitivity
SSEA4 (MC813) Mouse mAb detects endogenous levels of SSEA4 antigen.
Source / Purification
Monoclonal antibody is produced by injecting animals with human embryonal carcinoma 2102Ep cl.2A6 cells.
Confocal immunofluorescent analysis of NTERA2 cells using SSEA4 (MC813) Mouse mAb (green). Actin filaments have been labeled with DY-554 phalloidin (red). Blue pseudocolor = DRAQ5™ (fluorescent DNA dye).
SSEA4 (stage-specific embryonic antigen 4) is a glycolipid carbohydrate epitope expressed on the surface of human teratocarcinoma stem cells, human embryonic germ cells, and human embryonic stem cells (1). Expression of human SSEA4 decreases following differentiation of human embryonal carcinoma cells. Expression of the SSEA4 antigen is absent in murine pluripotent cells, but increases following differentiation (1,2).
- Krupnick, J.G. et al. (1994) Int J Cancer 59, 692-8. Applications: Fluorescent Detection, IC-IF.
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This product is intended for research purposes only. The product is not intended to be used for therapeutic or diagnostic purposes in humans or animals.
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