NUP98 (C39A3) Rabbit mAbProduct information
Product Pathways - Cytoskeletal Signaling
NUP98 (C39A3) Rabbit mAb #2598
|2598S||100 µl (10 western blots)||---||In Stock||---|
|2598T||20 µl (2 western blots)||---||In Stock||---|
|2598||carrier free and custom formulation / quantity||email request|
|W||1:1000||Human, Mouse, Rat, Monkey||Endogenous||98||Rabbit IgG|
Species cross-reactivity is determined by western blot.
Applications Key: W=Western Blotting, IP=Immunoprecipitation, IF-IC=Immunofluorescence (Immunocytochemistry)
Specificity / Sensitivity
NUP98 (C39A3) Rabbit mAb detects endogenous levels of total NUP98 protein.
Source / Purification
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro671 of human NUP98.
Western blot analysis of cell extracts from various cell types using NUP98 (C39A3) Rabbit mAb.
Nucleoporin 98 kDa (NUP98) is a component of the nuclear pore complex. It is expressed as three different precursors that undergo auto-cleavage to generate a common amino-terminal 98 kDa peptide (NUP98) and carboxy-terminal 6, 96 (NUP96) and 88 (p88) kDa peptides (1,2). NUP98 contains FG and GLFG repeat domains at its amino terminus and a RNA-binding domain in its carboxy terminus (3). The NUP98 gene is localized on chromosome 11p15.5, a region frequently rearranged in leukemias. To date, 15 fusion partners have been identified for NUP98 (4,5).
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This product is intended for research purposes only. The product is not intended to be used for therapeutic or diagnostic purposes in humans or animals.
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U.S. Patent No. 7,429,487, foreign equivalents, and child patents deriving therefrom.