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Horizon is a leading provider of genetically defined, human genomic reference standards, including Formalin-Fixed Paraffin-Embedded (FFPE) cell line sections and purified genomic DNA (gDNA). HDx™ Reference Standards offer a sustainable source of reference material to laboratories, proficiency schemes and manufacturers, providing an unprecedented level of control.
Drawing upon our proprietary genome editing platform, we engineer clinically relevant cancer genes in human cell lines, exactly as they occur in patient tumors. In this way we are able to define virtually every characteristic of our reference standards, from the molecular constitution of the genome to DNA output associated with each product batch. These standards have been made available in a variety of formats including gDNA aliquots, FFPE slices, Fluorescence In Situ Hybridization (FISH) material and Immunohistochemistry (IHC) assays.
HDx Reference Standards are already having a profound impact on the molecular laboratories that have adopted them:
BIOKÉ is the exclusive distributor of Horizon Diagnostics in The Netherlands.