Fluidigm

High-throughput RT-PCR, digital PCR, genotyping and Next Generation sequencing applications on nano-volume scale using proprietary Integrated Fluidic Circuits (IFC's).
 

Company Profile

Fluidigm Corporation develops and distributes systems based on the unique properties of Integrated Fluidic Circuits (IFCs) to precisely control fluids on a nano volume scale. The company's vision is to create and to lead a new industry in which IFCs bring unparalleled efficiencies to the life science and allied fields.

The BioMark HD system sets the new standard for high throughput real-time PCR assays and streamlines workflow for applications demanding sensitivity and dynamic range, at extremely high throughput.

The C1 Single-Cell Auto Prep System is the world’s first commercially available, automated single-cell isolation and preparation system for genomic analysis.

The EP1 system sets the new standard for high throughput SNP genotyping and provides superior data quality with a fast and easy workflow and can also be used for end point digital PCR applications.

The Access Array Integrated Fluidic Circuit (IFC) facilitates parallel amplification of 48 unique samples, in effect preparing 48 sequencing libraries, in just a few hours.


Application
 

Gene Expression

  • High throughput
  • Low cost
  • Compatibility with existing reagents

Single-Cell Genomics

  • Cell Differentiation
  • Biomarker discovery
  • Circulating tumor cells
  • Drug candidate screening/efficacy

Single-Cell mRNA Sequencing Single-Cell Gene Expression Single-Cell miRNA Expression 

SNP Genotyping

  • Higher sample throughput
  • Outstanding data quality
  • Dramatically lower costs 

Targeted Resequencing

  • Target enrichment
  • Sample barcoding for multiplexed sequencing
  • Sequencing library preparation using amplicon tagging 

Sample Quantitation

  • Ability to amplify individual molecules
  • Accurately and reproducibly determine library concentrations 

Copy Number Variation

  • High-resolution CNV studies using digital PCR
  • Simple, fast, and reliablejavascript:showWysiwyg('description'); workflow
  • Standard assays and reagents

Digital PCR

  • Eliminate false positives