Product Pathways - Metabolism
PANK2 Antibody (Mouse Specific) #6923
|6923S||100 µl (10 western blots)||---||In Stock||---|
|6923||carrier free and custom formulation / quantity||email request|
Species cross-reactivity is determined by western blot.
Applications Key: W=Western Blotting
Specificity / Sensitivity
PANK2 Antibody (Mouse Specific) recognizes endogenous levels of total PANK2 protein.
Source / Purification
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of mouse PANK2 protein. Antibodies are purified by protein A and peptide affinity chromatography.
PANK2, pantothenate kinase 2, catalyzes the first step in CoA biosynthesis (1,2). Human PANK2 is located in the mitochondria, and research studies have shown some mutations in human PANK2 are linked to neurodegeneration (2). Alternatively, mouse PANK2 localizes in the cytosol, and defective PANK2 in mice leads to retinal degeneration (1,3).
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This product is intended for research purposes only. The product is not intended to be used for therapeutic or diagnostic purposes in humans or animals.
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