Product Pathways - Ca / cAMP / Lipid Signaling
ApoA1 (5F4) Mouse mAb #3350
|3350S||100 µl (10 western blots)||---||In Stock||---|
|3350||carrier free and custom formulation / quantity||email request|
Species cross-reactivity is determined by western blot.
Applications Key: W=Western Blotting, IP=Immunoprecipitation
Specificity / Sensitivity
ApoA1 (5F4) Mouse mAb detects endogenous level of total ApoA1 protein.
Source / Purification
Monoclonal antibody is produced by immunizing animals with a full-length recombinant human ApoA1.
Western blot analysis of decreasing concentrations of ApoA1 protein purified from human serum using ApoA1 (5F4) Mouse mAb.
ApoAI (Apolipoprotein A1) is a major component of high density lipoprotein (HDL, the “good cholesterol”) in plasma. It is produced in the liver and small intestine. ApoA1 is a cofactor for lecithin cholesterolacyltransferase (LCAT) that is responsible for the formation of plasma cholesteryl esters and promotes cholesterol efflux from tissues to the liver for excretion. Defects in ApoA1 are associated with high density lipoprotein deficiency (HDLD) and systemic non-neuropathic amyloidosis (1-3).
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This product is intended for research purposes only. The product is not intended to be used for therapeutic or diagnostic purposes in humans or animals.
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