Powerfully simple workflow for label-free cell sorting.

LevitasBio is advancing science and human health by providing researchers with a new and powerful method of cellular analysis. Magnetic levitation is the first truly novel approach to cellular analysis in 30 years. Extensive research has shown that cells of different types or states have unique physical signatures, levitating in predictable ways. Here’s how it works.

The LeviCell delivers a simple, label-free cell separation in a fast, reliable, and gentle solution to sort all types of cell populations. Thus, the LeviCell enables studies and beneficial uses of previously inaccessible, high-value primary samples, and sensitive cell types. Separation works regardless of the starting cell number, viability, or sensitivity to processing.

 

 

 

Simplified Workflow

Sort smarter, not harder. With LeviCell, you can drastically reduce the time and manual steps required to sort and treat your samples.

Untouched, label-free cells

Live cells in. Live cells out. Free of dyes and antibodies, the LeviCell is simply kinder to your samples.

Any size, Any type.

From small to large cells and embryos and C. elegans, no cell is too sensitive or difficult. See all cells and samples tested.

 

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Your cells deserve more than two FACS.

• No aerosols or sample-to-sample cross-contamination; 100% of the sample remains in the consumable

• Low-pressure (<1psi) fluidics with low shear stress mean no stress to the cells

• Two fluorescence excitation sources in addition to bright field illumination

• Compact format allows it to fit under standard hood or biosafety cabinet

• Flow rates and collection ratios are user-adjustable via the control software

• No run-to-run calibration or clean-up is required, further improving ease of use compared to standard approaches

• Large feature sizes help prevent clogging, so no prior debris removal is required

• Incorporated image capture and analysis software allows users to analyze cell population density and distribution, and interrogate basic morphology.

 

The LeviCell cartridge S2.1

The LeviCell cartridge is a single-use consumable designed to work with the LeviCell 1.0. By containing the entire sample path onboard, it prevents sample to sample cross-contamination issues and negates any cleaning requirements between runs.

How It Works

Magnetic levitation is the first truly novel approach to cellular analysis in 30 years. Extensive research has shown that cells of different types or states have unique physical signatures, levitating in predictable ways when they encounter a magnetic density field. Here’s how it works.

	STEP 1 Sample Introduction Dispense a sample of mixed cells (or cells to be analyzed) into the single use consumable. Cells flow into the analysis channel and are levitated.
STEP 2 Magnetic Levitation By flowing cells through a channel surrounded by magnets, LevitasBio technology separates individual cells according to type or state based on the different levitation heights caused by the unique physical properties.
	STEP 3 Stabilization & Measuring The different cell types stabilize at different levitation heights. As the sample flows through the system, different cell types are analyzed and collected.
STEP 4 Cell Separation By continuing to aspirate the sample, the levitated cells transition to a bifurcation that separates cells into the different ports on the consumable.
	STEP 5 Collection The separated cell populations are then pipetted out of the consumable.

 

Download the PNAS publication on magnetic levitation of single cells.

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Applications

You will be forwarded to the website of Levitas Bio.

• Live Cell Enrichment
• Single Cell Sequencing
• Tissue Processing
• Tumor Processing
• Unbiased Sample Enrichment
• Antibiotic Testing
• Nuclei

 

 

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